Results
First Call (2003)
• Nanosized multicatalytic objects for cascade reactions in multistep synthesis
prof. dr. ir. J.C.M. van Hest, KUN; dr. A.E. Rowan, KUN; dr. N.A.J.M. Sommerdijk, TUE; prof. dr. R. Wever, UVA; dr. J.N.H. Reek, UVA
• Nitrogen heterocycles from aldehydes via biocatalytic cascades
prof. dr. F.P.J.T. Rutjes, KUN; dr. J. van der Oost, WUR; dr. ir. M.C.R. Franssen, WUR; prof. dr. ir. A.P.G. Kieboom, UL
• Use of sulfatases in the production of sulfatated carbohydrates and steroids
prof. dr. R. Wever, UVA; dr. F.L. van Delft, KUN; prof. dr. H. Hiemstra, UVA
• Highly functionalised enantiopure epoxides and epoxide derived products by cascade bio- and homogeneous catalysis in table-top reactors
prof. dr. J.G. de Vries, RUG; prof. dr. B.L. Feringa, RUG; prof. dr. ir. H.J. Heeres, RUG; prof. dr. D.B. Janssen, RUG; prof. dr. ir. A.J. Minnaard, RUG
• Selective redox biocatalysts for oxidative activation of biomolecules (BIOREDOX)
prof. dr. D.B. Janssen, RUG; dr. W.J.H. van Berkel, WUR; dr. ir. M.W. Fraaije, RUG; prof. dr. ir. A.P.G. Kieboom, UL
• Cell and enzyme engineering for the construction of integrated biocatalysts performing sterol-steroid biotransformations
prof. dr. D.B. Janssen, prof. dr. L. Dijkhuizen, dr. R. van der Geize, RUG
• CefFerm
prof. dr. A.J.M. Driessen, prof. dr. M. Veenhuis, prof. dr. D.B. Janssen, RUG; prof. dr. J. Pronk, TUD
• Catalytic cascade reactions for selective oxidations with benign oxidants
prof. dr. R.A. Sheldon, TUD; prof. dr. I.W.C.E. Arends, TUD; prof. dr. W.R. Hagen, TUD; prof. dr. S. de Vries, TUD
• High throughput screening of micro organisms in "Fed batch on a chip"
prof. dr. ir. J.J. Heijnen, prof. dr. G.W.K. van Dedem, prof. dr. ir. L.A.M. van der Wielen, dr. M. Ottens, TUD; prof. dr. ir. A. van der Berg, dr. H. Gardeniers, UT
Second Call (2007)
• A cell factory for the biosynthesis of complex peptides (CELLPEP)
Prof. dr. I.J. van der Klei (RUG); Prof. dr. A.J.M. Driessen (RUG); Prof. dr. ir. J.J. Heijnen (TUD); Prof. dr. J.T. Pronk (TUD)
• Industrially relevant heterocycles through biocatalytic cascades
Prof. dr. F.P.J.T. Rutjes (RU); Dr. M.C.R. Franssen (WUR); Prof. dr. J. van der Oost (WUR): Prof. dr. R. Wever (UvA)
• Biocatalytic exploitation of monooxygenases (BIOMOX)
Prof. dr. ir. M.W. Fraaije (RUG); Prof. dr. W.J.H. van Berkel (WUR); Prof. dr. ir. L. Dijkhuizen (RUG); Prof. dr. N.P.E. Vermeulen (VU)
• Chemoenzymatic peptide synthesis
Prof. dr. D.B. Janssen (RUG); Prof. dr. F.P.J.T. Rutjes (RU); Prof. dr. ir. J. Tramper (WUR)
• Development of conditional protein-ligand exchange applied to immune technology
Dr. H. Ovaa (NKI); Dr. B. Rodenko (NKI); Prof. dr. T.N.M. Schumacher (NKI)
SME First Call (2007)
• Enzymatic synthesis of enantio- and diastereomerically pure unsaturated beta-hydroxy-alfa-amino acids and synthetic elaboration into biologically relevant derivatives
Prof. dr. F.P.J.T. Rutjes (RU); Prof. dr. J. van der Oost (WUR); Prof. dr. R. Wever (UvA); Dr. R.H. Blaauw (Chiralix BV)
• Plants as cell factories
Prof. dr. R. Verpoorte (UL); Prof. dr. J. Memelink (UL); Dr. A.E. Schulte (UL); Dr. G.P. Platenburg (Prosensa BV)
• Combining Cross Linked Enzyme Aggregates with Multi-Component Reactions for the efficient preparation of fine chemicals
Dr. U. Hanefeld (TUD); Prof. dr. ir. R.V.A. Orru (VU); Prof. dr. R.A. Sheldon (CLEA Technologies)
• Industrial chicory as fine-chemical production platform
Prof. dr. ir. H.J. Bouwmeester (WUR); Prof. dr. H.J. Bosch (Plant Research International); Dr. M.C.R. Franssen (WUR); Dr. H. Jansen (Dafra Pharma BV)
SME Second Call (2007)
• Dynamic assemblies by dynamic kinetic resolution
Prof. dr. E.W. Meijer (TU/e); Dr. ir. A.R.A. Palmans (TU/e); Dr. ir. H.M. Janssen (SyMoChem BV)
• Polymersome nanoreactors for enzymatic screening and biotransformation
Prof. dr. ir. J.C.M. van Hest (RU); Prof. dr. J.J.L.M. Cornelissen (UT); Dr. M. Nallani (RU); Prof. dr. R.J.M. Nolte (RU); Prof. dr. A.E. Rowan (RU); Dr. D.M. Vriezema (Encapson BV)
SME Third Call (2008)
• Cytochrome P450 BM3 mutants: Towards Highly Efficient Stereoselective Biocatalysts (BM-STEREO)
Prof. dr. N.P.E. Vermeulen (VU); Dr. J.N.M. Commandeur (VU); Drs. T. Janssen (Isobionics BV)
• The use of plant P450s in microbial hosts for the production of fine-chemicals
Prof. dr. ir. H.J. Bouwmeester (WUR); Prof. dr. H.J. Bosch (UU); Drs. T. Janssen (Isobionics BV)
SME Fourth Call (2009)
• A biotechnological process for the production of (+)-carvone
Prof. dr. ir. M.W. Fraaije (RUG); Dr. W. duetz (EnzyScreen BV)
• Novel laccases and their enhanced expression in Aspergillus niger
Dr. ir. L.H. de Graaff (WUR); Dhr. P.V. Schut (ProteoNic BV)